ISSN.
Bali Medical Journal (BMJ) 2012.
Volume 1.
Number 1:36-39 Pregnancy Exercise Increase Enzymatic Antioxidant In Pregnant Women Wagey.
Obstetric and Gyneocology Department.
Faculty of Medicine Sam Ratulangi University/ Prof.
Kandou General Hospital Manado-Indonesia Biomedicine Postgraduate Program Udayana University.
Bali-Indonesia Objectives: Pregnancy is a vulnerable condition to all kinds of "stress", resulting in changes of physiological and metabolic functions.
This research aims to determine effect of exercise during pregnancy in increasing enzymatic antioxidant marked by increase of superoxide dismutase (SOD), gluthation peroxidase (GSHP.
, and catalase (CAT) Methods: Randomized pre and posttest control group design was employed in this study.
A number of 66 pregnant women were recruited in this study and grouped into two groups, i.
e 30 of them as control group and the rest as treatment group.
Pregnancy exercise was performed to all 36 pregnant women from 20 weeks gestation on treatment The exercise was performed in the morning for about 30 minutes, twice a weeks.
On the other hand, daily activities was sugested for control group.
StudentAos t-test was then applied to determine the mean different of treatment and control group with 5 % of significant value.
Results: This study reveals that there were significantly higher increase of .
uperoxide dismutase (SOD), gluthation peroxidase (GSHP.
, and catalse (CAT) levels of treatment group compare to control group.
These enzymatic antioxidant increase among these two group were around 1.
36 Ag/gHb for SOD.
14 IU/gHb for GSHPx.
IU/gHb for CAT, .
< 0.
Clinical outcomes, such as strengten of pelvic muscle and quality of life of treatment group were significantly better compared to control group .
< 0.
Conclusions: This means that exercise during pregnancy ages of 20 weeks increase enzymatic antioxidant levels SOD.
GSHPx, and CAT higher compare to control group without exercise.
Keywords: oxidative stress, superoxide dismutase, gluthation peroxidase, catalase Corespondence: Wagey.
Address: Obstetric and Gyneocology Department.
Faculty of Medicine Sam Ratulangi University/ Prof.
Kandou General Hospital Manado-Indonesia delivery time.
7 Exercise for pregnant women can affect fetal growth in uterus.
Sports activities should be accompanied by an adequate energy supply.
The energy needed by the body when doing sports produced by the mitochondria.
The locus of the catabolism, metabolism and oxidation reactions within the cells is mitochondria.
The reaction in the mitochondria will generate the energy needed by the Exercise during pregnant is beneficial for some extents involving, diabetic prevention and glycemic control improvement in pregnant women with diabetes, protective effects against heart disease, osteoporosis, hypertension, reducing the risk of colon and breast cancer, and can reduce body fat.
8 Common complaints during pregnancy, such as fatigue, varicosities, swelling of extremities, insomnia, stress, anxiety, and depression can also be reduced by 9 Scientific evidence also shows that by exercising during pregnancy can reduce labor time .
ength of labo.
and reduce complications of 8,10 Other studies also find that the birth process was significantly associated with pregnancy exercise execution, the mothers who take pregnancy exercise proved to be through the birth process smoother and faster than no pregnancy exercise.
This research was conducted to determine the effect of exercise during pregnancy in increasing Open access: w.
INTRODUCTION
Pregnancy is a condition that is vulnerable to all kinds of "stress", resulting in changes of physiological and metabolic functions.
In pregnancy there is an increasing in energy and oxygen 1,2 In addition, the placenta is in fact contains many mitochondria which increases the oxidative metabolism to produce energy.
These metabolic processes increase the use of oxygen and when oxygen available is not used maximum, it can cause the formation of oxidative stress and excessive free radicals that affect the continuity of pregnancy.
Nowdays, the role of decreasing antioxidants and the increase of oxidants or free radicals in pregnant women has been widely studied.
It is important to follow the development of pregnancy.
The imbalance between antioxidants and free radicals in pregnancy causing pathological changes that can lead to complications in pregnancy.
Antioxidants and oxidants biochemical marker are very useful in observing the complications that may arise in 1,2,4,5,6 Physical training or exercise in pregnancy can maintain excess body weight, preventing diabetes, hypertension, and shorten the Bali Medical Journal (BMJ) 2012.
Volume 1.
Number 1:36-39 ISSN.
enzymatic antioxidant, marked by increase of SOD.
GSHPx, and CAT levels.
METHODS AND PATIENTS
This study is employing a randomized experimental, using pretest-posttest control groups A number of 66 pregnant women were admited in this study and grouped to two groups, i.
30 of them as control group and the rest as treatment Pregnancy exercise was performed to all 36 pregnant women from 20 weeks gestation on treatment group.
The exercise was performed in the morning for about 30 minutes, twice a weeks.
On the other hand, daily activities was sugested for control StudentAos t-test was then applied to determine the mean different of treatment and control group with 5 % of significant value.
RESULTS
Subject Characteristics In this study, 66 pregnant women were recruited, 30 of them were studied as control group and 36 as treatment group.
Characteristics of research subjects can be seen in Table 1.
Table 1 Characteristics of Research Subjects Clinical Characteristics Age .
Education SLTP
SLTA
Occupation IRT
Swasta
PNS
MHS
Hb .
/dL) Average Minimum Maximum Treatment Group (N = .
Control Group (N = .
61 A 0.
89 A 1.
SD = Elementary School.
SLTP = Yunior High School.
SLTA = Senior High School.
PT = University.
IRT = servant.
Swasts = private.
PNS = civil servant.
MHS = students.
using the explore facilities of SPSS for Windows.
The data content of SOD.
GSHPx, and CAT are in normal distribution and also homogeneous with p> 05, as presented in Table 2a,b.
Table 2a Data Pretest of SOD.
GSHPx, and CAT Levels in Control and Treatment Group Parameter SOD (Ag/gH.
Average Minimum Maximum p normality GSHPx (IU/gH.
Average Minimum Maximum p normality CAT (IU/gH.
Average Minimum Maximum p normality Treaatment Group .
Pretest Control Group .
Pretest 30A0.
54A0.
32A0.
53A0.
18A0.
38A0.
Table 2b Data Posttest of SOD.
GSHPx, and CAT Levels in Control and Treatment Group Parameter SOD (Ag/gH.
Average Minimum Maximum p normality GSHPx (IU/gH.
Average Minimum Maximum p normality CAT (IU/gH.
Average Minimum Maximum p normality Treaatment Group .
Posttest Control Group .
=30 Posttest 53A0.
17A0.
57A0.
42A0.
18A0.
22A0.
Increased Levels of Superoxide dismutase (SOD).
Glutathione peroxidase (GSHP.
and catalase (CAT) Test of normality and homogeneity of data distribution levels of SOD.
GSHPx, and CAT was performed using Shapiro Wilk test and Levene's Test at the significance level (A) of 0.
This is done Analysis of differences in the effect of treatment without any pregnancy exercise and with pregnancy exercise against increased levels of SOD.
GSHPx, and CAT is carried out by analyzing the data of post test SOD.
GSHPx, and CAT levels in control group and treatment group.
This can be applied by using independent t-test.
It was found that the posttest data Open access: w.
Bali Medical Journal (BMJ) 2012.
Volume 1.
Number 1:36-39 ISSN.
of SOD.
GSHPx, and CAT level on control group was significantly different to treatment group as shown with p values<0.
Resume of the results of analysis are presented in Table 3.
Table 3 Summary Results of The Average Difference in SOD.
GSHPx, and CAT levels post test of Control Group and Treatment Group Different Parameter Average SOD (Ag/gH.
Control Treatment - 1.
-1,06
GSHPx (IU/gH.
Control Treatment - 1.
CAT
(IU/gH.
Control Treatment - 0.
SD = standard deviation, p = significance.
CI = confidence interval.
SOD = superoxide dismutase.
GSHPx = gluthation peroxidase.
CAT = catalase.
DISCUSSION