Jurnal Ilmu Farmasi dan Farmasi Klinik (JIFFK) Vol. No. Juni 2024. Hal. ISSN: 1693-7899 e-ISSN: 2716-3814 QUALITY OF LIFE AND COMPLIANCE BASED ON HYPERTENSION PATIENT CHARACTERISTICS AT KROBOKAN PRIMARY HEALTH CENTER WEST SEMARANG DISTRICT Gilang Rizki Al Farizi*. Rissa Maharani Dewi. Fransica Gloria. Hartika Widiya Undergraduate of Pharmacy. STIKES Telogorejo. Semarang. Central of Java. Indonesia *Email: gilang_rizki@stikestelogorejo. Received: 31-05-2023 Accepted:15-02-2024 Published:30-06-2024 INTISARI Hipertensi merupakan penyakit kronis yang menjadi masalah kesehatan di Indonesia. Menurut Riset Kesehatan Dasar 2018 populasi hipertensi di Indonesia berada pada sekitar 34,1 % pada usia Ou18 Setiap tahunnya penderita hipertensi semakin meningkat sekitar 29% orang dewasa menderita hipertensi diseluruh dunia. Penderita hipertensi membutuhkan terapi yang lama bahkan seumur hidup yang tentunya membuat pasien terus Ae menerus mengkonsumsi obat antihipertensi yang akhirnya dapat berpengaruh terhadap kepatuhan pasien dan kualitas hidup. Penelitian ini bertujuan untuk mengetahui gambaran kualitas hidup dan kepatuhan berdasarkan karakteristik pasien hipertensi di Puskesmas Krobokan Semarang Barat. Penelitian ini menggunakan rancangan kuantitatif dengan jenis penelitian observasional dan pengambilan data secara cross sectional yang dilakukan pada periode bulan Maret AeMei tahun 2023. Instrumen yang digunakan yaitu MMAS-8 dan HRQOL SF36 dengan jumlah 53 responden yang memenuhi kriteria inklusi. Hasil penelitian didapaptkan karakteristik responden tertinggi adalah Wanita 36 . %), usia 56 Ae 65 tahun 26 . %). SMA 18 . %), ibu rumah tangga 31 . %), lama menderita hipertensi Ou 2 tahun 27 . %), 1 jenis obat yang dikonsumsi 50 . %), menderita penyakit lain 23 . %) dan kepatuhan sedang 36 . %). Kualitas hidup pada domain energi, peran emosi, peran fisik, fungsi fisik dan kesehatan umum memiliki kualitas hidup yang rendah paling banyak pada pasien dengan kepatuhan sedang Kata kunci: Hipertensi. Karakteristik. Kepatuhan. Kualitas Hidup ABSTRACT Hypertension is the chronic diseases that is a health problem in Indonesia. According to the Basic Health Research 2018 the hypertension population in Indonesia is around 34. 1% at the age of Ou18 Every year hypertension sufferers are increasing, around 29% of adults suffer from hypertension worldwide. Patients with hypertension require long therapy even for life which certainly makes patients continuously consume antihypertensive drugs which can ultimately affect patient compliance and quality of life. The purpose of the study was to determine description of quality of life and adherence based on hypertention patient at Krobokan Primary Health Center. West Semarang district. This study used a quantitative design with observational research and a cross-sectional approach conducted in the period March-May 2023. The instruments used were MMAS-8 and HRQOL SF-36 as many as 53 samples who met the inclusion criteria. The results showed that the highest respondent characteristics were female 36 . %), age 56 - 65 years 26 . %), high school 18 . %), housewives 31 . %), length of hypertension Ou 2 years 27 . %), one of hypertention drug taken 50 . %), suffering from other illnesses 23 . %) and moderate adherance 36 . %). In the domains of energy, emotional role, physical role, physical function and Journal homepage:http:/w. id/publikasiilmiah/index. php/ilmufarmasidanfarmasiklinik ISSN: 1693-7899 general health had a low quality of life in most patients with moderate adherence Keywords: Adherence. Characteristics. Hypertension. Quality of Life *corresponding author: Nama : apt. Gilang Rizki Al Farizi. Farm Institusi : Sekolah Tinggi Ilmu Kesehatan Telogorejo Semarang Alamat institusi : Jl. Anjasmoro Raya. Tawangmas. Kec. Semarang Barat. Kota Semarang Jawa Tengah E-mail : gilang_rizki@stikestelogorejo. BACKGROUND Hypertension is a condition where increased blood pressure both systolic and diastolic Ou 140/90 mmHg (Paul AJ et. According to the World Health Organization in 2015, about 13 billion people in the world suffer from hypertension. In Southeast Asia, hypertension is one of the risk factors that cause 1. 5 million deaths per year (Woodham N et. In the National Health Report RISKESDAS, the hypertension population in Indonesia was around 34. 1% at the age of Ou18 years (Ministry of Health Republic Indonesia. , 2018. Williams B et. Hypertension is still the biggest problem for health, especially for people with hypertension. Most hypertensive patients consider the disease a mild disease that is often experienced, because most hypertensive diseases occur without any definite signs and symptoms such as headaches, weakness, fatigue, dizziness, anxiety and muscle weakness so that hypertensive patients consider the disease that often occurs is common. Every year hypertension sufferers are increasing about 29% of adults suffer from hypertension worldwide (Dewi F and Mulyani E, 2. This is because most people with hypertension do not know the impact and prevention that must be done by people with hypertension. Quality of life is an individual's perception of their position in life within the context of the culture and value system in which they live and in relation to goals, expectations, standards and An individual's quality of life is associated with a description of an individual's maximum physical health, psychological state, level of independence, social relationships and trust. (World Health Organization, 2. A person's health status or quality of life is assessed by several aspects, namely: 1. Subjective quality of life is how good a person's life feels. Existential quality of life assesses how good one's life is on a deeper or specific level. Objective quality of life is assessed by how one's life is perceived by the outside world such as the environment (Teoli D and Bhardwaj A. , 2. Quality of Life Domain Mental Wellness Physical Wellness General Health Physical Role Mental Health Energy Physical Function Soreness Role of Emotions Social Role Figure 1. Quality of Life Domain Short Form 36 (SF-. is one of the generic instruments used to measure a person's quality of life. The SF-36 consists of 8 domains that describe a person's quality of life from physical health and mental health. (Brazier JE et. Several factors affect a person's quality of life such as: gender, age, education, employment, marital status, self-efficacy, depression as well as social support and motivation. (Okello S et. Based on the description above, it is necessary to conduct research on analyzing the relationship between characteristics and quality of life of hypertensive patients. Quality of LifeA(Al-Farizi et al. , 2. ISSN: 1693-7899 METHOD Study Design This study used a quantitative design with observational research type and cross sectional approach conducted in the period of March-May 2023 at Krobokan Primary Health Center. West Semarang district. This research has been approved by the Ethics Committee of STIKES Telogorejo Semarang with No. 055/IV/KE/STIKES/2023, to conduct clinical research related to patients at Krobokan Primary Health Center. West Semarang district. The research was conducted in accordance with the Code of Ethics Guidelines. The inclusion criteria was respondents are members of prolanis who suffer hypertention and are over 18 years old, all respondents received hypertention theraphy and suffering from hypertention at least two mounths . Research Samples 60 Individuals Inclusion 53 Individuals Exclusion 7 Individuals Did not complete the questionnaire: 3 Individuals Not willing to participate in the study: 4 Individuals Figure 2. Sample of Research Variable and Instrument The research instrument used a questionnaire Morisky Medication Adherence Scale Ae 8 (MMAS-. from Krousel-Wood M . and Short Form Ae 36 (SF-. from Nasar AS et. then translated it with Bahasa which has been tested for validity and reliability. The sample used was 53 respondents who met the inclusion criteria and continued to process data analysis using SPSS Version 16 for univariat data. RESULT AND DISCUSSION In this study, demographic data of respondents with hypertension were obtained in the form of age, gender, education level, occupation, duration of hypertension, number of hypertension drugs consumed and other diseases suffered. Based on Table I, there were 53 patients with hypertension at Krobokan Health Center. West Semarang, consisting of 17 male patients . %) and 36 female patients . %). Non-compliance in the use of antihypertensive drugs can have an impact on the patient's (Gardezi KM et. Several factors influence adherence such as: age, education, occupation, accommodation, family support and improving health worker interactions with patients (Pristianty L et. Education about information on the use of hypertension drugs by health workers has a positive impact on patients to undergo regular treatment so that the level of compliance will increase (Oktanti D et. In addition to education from health workers, family support is a supporting factor for adherence to drug use for hypertensive patients. Patients who get support from family or people closest to them will have an impact on hypertension patients to comply with their treatment (Pristianty L et. Table II below shows that patients suffering from complications of 1 type of disease are mostly diabetes mellitus around 12 patients . %) and dyspepsia 4 patients . %), while complications of more than 1 type of disease such as gout and hipercholesterolemia are 2 patients . %) as well as diabetes mellitus and hipercholesterolemia 2 patients . %). Some hypertensive patients at the Krobokan Primary Health Center in West Semarang district did not only suffer from 1 type of comorbidity, but 2 comorbidities or 3 comorbidities. JIFFK Vol. No. Juni 2024. Hal. ISSN: 1693-7899 Tabel I. Hypertension Patient Frequency Distribution Characteristic Frequency (N= . Percentage (%) Gender Male Female Age 26-35 years old 36-45 years old 46-55 years old 56-65 years old Education No education Elementary Junior high Senior high Diploma Bachelor Occupation Housewives Entrepreneur Private employee Civil servants Length of Hypertension O 1 Year 1 - 2 Years Ou 2 Years Number of hypertension drugs taken 1 Drug 2 -3 Drugs Suffering from other illnesses Yes Adherance Moderate High 2,40 A 0,689 Tabel II. Hypertension Patient Frequency Distribution Characteristic Kinds of Illnesses Complications 1 Kind of Illness Dyspepsia Gout Diabetic Mellitus Hipercholesterolemia Stroke Complications More Than 1 Kind of Illness Gout & hipercholesterolemia Diabetes Mellitus & Gout Diabetes Mellitus & hipercholesterolemia hipercholesterolemia & Dyspepsia hipercholesterolemia & hipertriglycerides hipertriglycerides. Gout and hipercholesterol Frequency N= 53 Percentage (%) Quality of LifeA(Al-Farizi et al. , 2. ISSN: 1693-7899 Quality of Life Domains by Gender Legends : Kualitas life Domain Quality ofHidup Female Perempuan LakiMale - Laki 80 Primer Data, 2023 Note: SR = Sosial Role. E = Energy. ER = Energy Role. MH. Mental Health. P = Pain. PR = Physical Role. = Physical Function. GH. General Health Figure 3. Overview of Quality of Life Domain of Hypertension Patients Based on Gender Characteristics Quality of Life Domains by Age Hidup Kualitas Domain of life Quality Primary Data, 2023 Legends : 65 y. 65Ae Tahun 55 y. 55Ae Tahun 45 y. 45Ae Tahun 35 y. 35Ae Tahun Note: SR = Sosial Role. E = Energy. ER = Energy Role. MH. Mental Health. P = Pain. PR = Physical Role. = Physical Function. GH. General Health Figure 4. Overview of Quality of Life Domain of Hypertension Patients Based on Age Characteristics Figure 3 showed that men had a better quality of life than women in the domains of physical function, physical role, pain, mental health, energy and social role. In the domains of general health and emotional role, women have a better quality of life than men. In another case. Figure 4 showed that the age range of 26-35 years had a better quality of life in all quality of life domains than the other age ranges of 36 - 45 years, 46 - 55 years and 56 - 65 years. As age increases, it is associated with the aging process which results in physical and physiological changes in a person which also affects the decline in quality of life (Fransisca M et. Older hypertensive patients will experience a decrease in quality of life in the domains of physical function, physical role, pain and JIFFK Vol. No. Juni 2024. Hal. ISSN: 1693-7899 Hidup Kualitas Domain of life Quality Quality of Life Domain by Last Education Legends : Sarjana Bachelor Diploma Diploma SMA High School Junior High SMP Elementary Tidak Mengenyam No Education Pendidikan Note: SR = Sosial Role. E = Energy. ER = Energy Role. MH. Mental Health. P = Pain. PR = Physical Role. PF = Physical Function. GH. General Health Figure 5. Overview of Quality of Life Domain of Hypertension Patients Based on Age Characteristics Quality Of Life With Work Domain Legends: Hidup Kualitas of life Domain Quality Civil Servant PNS/TNI/POL Employee Swasta Private Entepreneur Wirausaha Ibu Rumah Housewives Tangga 100 Primary Data, 2023 Note: SR = Sosial Role. E = Energy. ER = Energy Role. MH. Mental Health. P = Pain. PR = Physical Role. PF = Physical Function. GH. General Health Figure 6. Overview of Quality of Life Domain of Hypertension Patients Based on Last Education Characteristics The quality of life domains with the characteristics of the last education in Figure 5 above show that graduates and diplomas on average have a good quality of life in each domain compared to high school, junior high school, elementary school and no education. In another case. Figure 6 civil servant/police and military (TNI/POLRI) have the highest quality of life in the domain of physical role, mental health and emotional role. Private employment status in the domain of physical function has a better quality of life than Civil Servant/TNI/POLRI, entrepreneur and housewives. A person with a high level of education will be able to control their own condition, manage and motivate themselves well, as well as be able to receive and process information obtained properly. Hypertensive patients who have poor emotional intelligence will affect their health conditions (Garg Quality of LifeA(Al-Farizi et al. , 2. ISSN: 1693-7899 and Agarwal, 2. Yulitasari BI et. also stated that education affects a person's response in seeking information about treatment and care for their health. Private employment status in the physical function domain has a better quality of life than civil servant/TNI/POLRI, entrepreneurs and housewives. Research by Huang W et. , stated that physical activity makes a person's quality of life index increase compared to someone who is not physically active. Quality of Life Domain with Length of Hypertension Suffering Hidup Kualitas Domain of life Quality Legends : > >2 2Tahun 1-2Tahun < <1 1Tahun Primary data, 2023 Note: SR = Sosial Role. E = Energy. ER = Energy Role. MH. Mental Health. P = Pain. PR = Physical Role. = Physical Function. GH. General Health Figure 7. Overview of Quality of Life Domain of Hypertension Patients Based on Characteristics of Length of Hypertension Suffering Quality of Life Domain with Hypertension Therapy Domain of life Hidup Quality Kualitas Legends : 2 2- -33Obat 1 1Obat Primary Data, 2023 Note: SR = Sosial Role. E = Energy. ER = Energy Role. MH. Mental Health. P = Pain. PR = Physical Role. PF = Physical Function. GH. General Health Figure 8. Overview of Quality of Life Domain of Hypertension Patients Based on Hypertension Therapy Characteristics Figure 7 above show that the longer a person suffers from hypertension, the lower their the quality of life especially in the domain of energy, energy role, pain, physical role, and general role. This research is in line with the research of Kaliyaperumal S et. which said that long suffering from hypertension will make patients experience a decrease in the quality of life in physical JIFFK Vol. No. Juni 2024. Hal. ISSN: 1693-7899 and psychological health, thus requiring lifelong care. In addition, long suffering from hypertension will also affect the quality of life of hypertensive patients in social roles. Increased blood pressure causes a decrease in vascularization in the brain, making patients unfocused, more irritable, and limiting themselves to socialize with others because of the discomfort they experience (Di Chiara T Figure 8 showed that the quality of life of hypertensive patients who used 2 - 3 types of drugs had a better quality of life than patients who used only 1 type of antihypertensive drug in the domains of general health, physical function, physical role, pain, mental health, emotional role and Quality of life domain with other diseases Domain of life Hidup Quality Kualitas Legends : Yes 80 Primary Data, 2023 Note: SR = Sosial Role. E = Energy. ER = Energy Role. MH. Mental Health. P = Pain. PR = Physical Role. PF = Physical Function. GH. General Health Figure 9. Overview of Quality of Life Domain of Hypertension Patients Based on Characteristics of Suffering from Other Diseases Figure 9 showed that hypertensive patients who did not suffer from other diseases had a better quality of life in all quality of life domains such as: general health, physical function, physical role, pain, mental health, emotional role, energy and social role compared to patients who suffered from other diseases. life Domain Quality of KualitasHidup Domain Overview of Adherence and Quality of Life by Category Category Compliance : High Moderate Categori Quality of Life: Perfect - High: 100 - 80 Average - Low:79 - 1 Note: SR = Sosial Role. E = Energy. ER = Energy Role. MH. Mental Health. P = Pain. PR = Physical Role. PF = Physical Function. GH. General Health Figure 10. Overview of Quality of Life Domain of Hypertension Patients Based on Characteristics of Adherance Quality of LifeA(Al-Farizi et al. , 2. ISSN: 1693-7899 Hypertensive patients who do not suffer from other diseases have a better quality of life in all quality of life domains such as: general health, physical function, physical role, pain, mental health, emotional role, energy and social role compared to patients who suffer from other diseases. Comorbidities suffered by hypertensive patients adversely affect the quality of life of patients (Pristianty L et. Al Farizi GR et. In addition, according to the researcher, other diseases that are suffered make hypertensive patients experience psychological problems such as emotional and limitations in some physical activities (Basu S et. Tilea I et. Puspitasari 2. CONCLUSIONS In gender characteristics, men have a good average quality of life compared to women in each domain. As age increases, the quality of life of hypertensive patients will decrease. Hypertensive patients who have the latest education at college have a better quality of life when compared to hypertensive patients who get education only up to formal education. Civil servant/TNI/POLRI have a better quality of life compared to other job characteristics. The longer hypertensive patients suffer from hypertension, the more the quality of life of hypertensive patients will decrease. The amount of hypertension therapy obtained by hypertensive patients affects the quality of life of hypertensive Other diseases suffered by hypertensive patients affect the quality of life of hypertensive Future research is expected to examine adherence and quality of life with other ACKNOWLADGEMENT I would like to thank Mr. Ade Kaloeti. Hum for his contribution in improving the English of this article REFERENCES