JKM : Jurnal Kesehatan Mahardika Vol. No. September 2022, pp. ISSN: 2355-0724. DOI: 10. 54867/jkm. A Narrative Review: Quintuple Helixs Model for Malaria Elimination in Indonesia Yura Witsqa Firmansyah, 2Maurend Yayank Lewinsca, 2Muhammad Fadli Ramadhansyah, 2Mirza Fathan Fuadi, 2Wahyu widyantoro, 3Devin Ahnaf Rana Rizqullah, 4Ahlun Najaa Nazzun Priyono Putro, 5Siti Nurhidayati, 5Henny Lestyorini, 5Wahyu Istining Rahayu, 6Abdul Chodir, 7Gusman Arsyad. Rafika, 9Oryza Filial Zulkarnain, 10Tri Suwanti Adicita Enviro Platform Indonesia. Indonesia. firmansyahyura@gmail. Masters in Environmental Health. Faculty of Public Health. Diponegoro University Bachelor of Law Studies Program. Faculty of Law. Sultan Agung Islamic University Diplomat i Sanitation. Department of Environmental Health. Health Polytechnic of the Ministry of Health Surabaya Center for Environmental Health and Disease Control Engineering (BBTKLPP). Surabaya Regional General Hospital (RSUD) Dr. Soetomo. Surabaya Health Polytechnic of the Ministry of Health Palu Masters in Health Promotion. Department of Occupational Safety and Health. Diponegoro University Center for Environmental Health and Disease Control Engineering (BBTKLPP). Surabaya Ngawi District Health Office ARTICLE INFORMATION ABSTRACT Received: May 23, 2022 Revised: June 16, 2022 Available online: September 12, 2022 Malaria continues to impact the health and economies of people around the world. Further steps need to be taken in accordance with the Global Technical Strategy for malaria to prevent malaria Quintuple helix model is an integrated effort that involves cross-sector in controlling malaria cases in an area. The implementation of the quintuple helix model is expected to be used as consideration and input for policy makers in an effort to achieve malaria elimination in Indonesia by 2030. The purpose of this study is to eliminate malaria in Indonesia with the quintuple helix model. This study uses a systematic review narrative method that is used to identify study topics selectively on interesting and recent issues. Malaria control in Indonesia is carried out using the national resilience approach. The results obtained from the academic aspect for malaria control must be met, both in terms of educational background qualifications, from the industrial aspect of the economic system included in the quintuple helix model, from the government aspect the control program must be compiled under the Ministry of Health, from the media aspect where the media is one of the an important index in the management of malaria in an area, and from an environmental aspect that aims to prevent, limit vector breeding and reduce mosquito contact with humans. The quintuple helix model is expected to be an innovation in malaria control in Indonesia. involving academia and social community, industry, government, environmental engineering, and the media. It is hoped that each sector can provide roles that are in accordance with their duties and KEYWORDS Keywords - Malaria - Narrative Review - Quintuple Helix CORRESPONDENCE Yura Witsqa Firmansyah Adicita Enviro Platform Indonesia Indonesia E-mail: firmansyahyura@gmail. This is an open access article under the CC BY-ND license. Witsqa Firmansyah. Yura, et. A Narrative Review: Quintuple Helixs Model for Malaria Elimination JKM : Jurnal Kesehatan Mahardika Vol. No. September 2022, pp. ISSN: 2355-0724. DOI: 10. 54867/jkm. (API) of malaria in Indonesia in 2010 reached 1. INTRODUCTION Malaria continues to impact the health and economies while in 2020 it was 0. 87 per 1,000 population(Indonesia, of people around the world. There were 229 million Indonesia is the second country with the highest malaria cases in 2019 spread across 87 malaria endemic number of cases in the WHO Southeast Asia region after Countries that account for 51% of malaria India. However, the number of cases remains at a high cases in the world are Nigeria . %). Democratic rate, especially in the last 3 years, namely 202,176 cases Republic of Congo . %). Uganda . %). Mozambique . , 250,628 cases . , and 226,364 cases . %) and Niger . %)(Organization, 2. Malaria . (RI, 2019. (RI, 2019. (Indonesia, 2. elimination is an effort to stop local transmission of Special eliminations for eastern Indonesia, such as malaria-causing parasites in certain areas. Further steps the provinces of Papua. West Papua. East Nusa Tenggara need to be taken in accordance with the Global Technical (NTT) are targeted to be achieved by 2030(Keputusan Strategy Menteri (GTS) transmission(Organization, 2. Kesehatan Republik 1405/Menkes/SK/XI/2002 Indonesia Nomor Persyaratan One of the principles in the GTS is that all countries Kesehatan Lingkungan Kerja Perkantoran dan Industri, can accelerate efforts towards elimination through a The achievement of district or city-level combination of interventions that are tailored to the local malaria elimination in Indonesia is 318 districts in context and involve multiple sectors. The quintuple helix 2020 with a target of 345 city districts in model is an integrated effort that involves cross-sectoral 2021(Kementerian Kesehatan Republik Indonesia, control of malaria cases in an area. The quintuple helix model is continuously promoted in critical decision making for managing malaria vectors and reducing chemical-based controls(Organization, 2. The quintuple helix model requires a holistic approach with an ecological strategy for vector control that does not harm the environment. The Quintuple helix model also involves local communities through existing social communities to convey information on matters related to malaria. In the quintuple helix model, capacity building of health resources is carried out with training and support to participate effectively in malaria prevention programs(Africa P. Germany P, 2. Good implementation of the quintuple helix model will be integrated into national and local health systems and with national malaria control programs. The trend of malaria in Indonesia tends to decrease Synergy in malaria control must still be the focus of the government during the current COVID-19 pandemic in order to achieve complete elimination by Comprehensive distribution of bed nets, public-private partnerships with chemists, training in effective medicine to reduce the prevalence of malaria and the likelihood of developing fever in children under five years of age(Abegunde D. Orobaton N. Bassi A. Oguntunde O. Bamidele M, 2. Community case management of malaria (CCM. using CHW-trained volunteers with RDT and ACT-based diagnostics in southern Congo is proving to be an acceptable approach to detect and treat malaria infection(Swana EK. Makan GY, Mukeng CK, Mupumba HI. Kalaba GM, 2. with the API indicator. The annual parasite incidence Witsqa Firmansyah. Yura, et. A Narrative Review: Quintuple Helixs Model for Malaria Elimination JKM : Jurnal Kesehatan Mahardika Vol. No. September 2022, pp. ISSN: 2355-0724. DOI: 10. 54867/jkm. The eastern region of Indonesia has a very high API, namely the provinces of Papua . West Papua and input for policy makers in an effort to achieve malaria elimination in Indonesia by 2030. and East Nusa Tenggara . per 1,000 Most of the provinces, namely 31 provinces METHODS . 2%) had malaria API < 1 per 1000 population. The This research is a systematic review research with the causes of high malaria in the case study in West Papua type of systematic review narrative, a systematic review are the difficulty of detecting the weather by the BMKG, narrative is used to identify research topics selectively on the symptoms of malaria are similar to mild illness, the interesting and current issues. The purpose of a difficulty of identifying the source of the infection, the systematic review is to obtain literacy studies that can be community environment favored by the Anopheles sp. used as a literature review or reference in descriptive or lot of puddles of wate. , and prevention of the lack of explanatory based studies. The articles used in this study community so that recovered people can be infected amounted to 15 articles with article filtering as below, again(Astin N. Alim A, 2. The implementation of IVM is expected to be used as material for consideration Scopus . Science Direct . ProQuest . SpringerLink . Google Scholar . Nature . JSTOR . Emerald Insight . Search articles using keywords. malaria and the quintuple helix . Final screening of articles based on inclusion criteria . Inclusion criteria: 2011-2021 publications Has a study of malaria research and the quituple heli x Articles can be accessed in full Articles does not use the review method Picture 1. Flow Chart Screening Article RESULTS AND DISCUSSION Academic and Social Community The ability of available human resources for malaria control must be met, both in terms of academic qualifications and educational background. Several planned programs and activities have been prepared by these human resources. All programs are relevant. Klambunization is a program that originates from community development(Tynan et al. , 2. Decision making based on the facts of the case studies has been well done. This case study is used in the treatment and eradication of malaria. An important fact that has not been used as a basis for action is the ecological data on malaria vectors. Ecological data can be used for malaria control(Campbell et al. , 2. An. An. An. maculatus dan An. through the provision of types and densities of vectors that have the potential to cause malaria infection. Four species in the study area were positive as vectors of An. An. Witsqa Firmansyah. Yura, et. A Narrative Review: Quintuple Helixs Model for Malaria Elimination JKM : Jurnal Kesehatan Mahardika Vol. No. September 2022, pp. ISSN: 2355-0724. DOI: 10. 54867/jkm. An. maculatus and An. The greater potential for malaria infection(Beier et al. , 2. the diversity of species as vectors, the higher the need for collaboration between the public sector. The degree of success lies in the use of available and industry, and the academic sector to align the education newly created 'knowledge' according to the Quintuple system with the needs of the labor market, but also to Helix Model(Keiser et al. , 2. Quintuple Helix is an encourage innovation. The peculiarity of this concept is innovation model that can overcome existing malaria that it shifts the position of stakeholders, from isolated or cases through the application of knowledge and bilateral, even trilateral forms of cooperation to the knowledge because it focuses on social exchange . and knowledge transfer within a particular country or nation-state subsystem (Michael et al. , 2. Considering that environmental-based malaria is Quintuple Helix's 'nonlinear' innovation model, which quite complex and locally specific, its control is unlikely to be successful if only carried out by a health approach. environment systems together into one 'interdisciplinary' Therefore, it is necessary to apply integrated control, and 'transdisciplinary' framework, can provide a step-by- namely a combination of several methods that are step model for understanding quality-based effective synergized and integrated in the malaria control program. development management, restoring balance with nature. This is because malaria transmission is a series of events and enable future generations to live in plurality and caused by the presence of parasites, mosquitoes as diversity on earth (Gu et al. , 2. vectors, the physical environment, and humans as hosts. know-how The quintuple helix model includes the relationship With this method, stakeholders, namely the industry between the academic community, industry, the public concerned, the community must actively take part sector, civil society, and the natural environment. In the through partnerships to help the industry to prevent quintuple helix model, it is emphasized that the natural This component is a chain of transmission of environment is the main habitat, so that cross-sectoral malaria, so that efforts to prevent and control malaria collaborative efforts are needed to support vector through breaking the chain of transmission are very eradication in the environment. The achievement of sustainable development is a must in the era of The HR factor is very large in regulating the entry globalization, digitalization, and rapid technological and exit of goods, maintaining the quality of goods and A dynamic balance is needed that will ensure controlling whether there are areas that run out of the process of interaction between the population and the In addition to paying attention to the HR factor, carrying capacity of its environment. another important thing in logistics is the existence of a Industry proper warehouse, both a drug warehouse and an The economic system belongs to the quintuple helix insecticide warehouse. Malaria Center has its own The economic system, as the second subsystem, consists of industry, companies, services, and banks. (Harijanto, n. This helix concentrates and focuses the economic capital Government . : entrepreneurship, machines, products, technology. Many control programs are structured under the money, etc. ) of a country . ation-stat. This explains the Ministry of Health, with no organizational links to other Witsqa Firmansyah. Yura, et. A Narrative Review: Quintuple Helixs Model for Malaria Elimination JKM : Jurnal Kesehatan Mahardika Vol. No. September 2022, pp. ISSN: 2355-0724. DOI: 10. 54867/jkm. government ministries . , environment, education, and Chwatt, 1. Community involvement is always agriculture, and touris. , municipal entities . ongoing but has not become part of the culture to free the community from mosquito bites. People are often not relationships with stakeholders in the community . alert, so they are bitten by Anopheles mosquitoes. The business, educators, community groups and NGO. Various techniques are being used to control mosquitoes, construction of houses are the main obstacles in isolating the spread of mosquitoes. The community has sufficient concerned with mosquito surveillance, basic information knowledge to understand the benefits of mosquito nets, on the ecology and behavior of vector species, or health but they prefer to feel comfortable than using the system data on disease. In addition, a common problem mosquito nets. Local wisdom dictates isolating patients is the lack of stable funding for mosquito control with bed nets until they are completely cured. It is operations and the lack of initiatives to exert influence in effective in controlling the spread of malaria between supporting mosquito control by government and other community entities. In this review, it is hoped that the The application of the quintuple helix model for quintuple helix model can replace the less effective IVM by evaluating the failure of the IVM. Collaboration between sectors to run effectively. There is Progress in implementing IVM continues to be slow. an assumption that malaria is the responsibility of the In the Institute of Medicine's review of Vector Infectious government, especially the ministry of health, while Diseases, it hinders our ability to find realistic solutions to the problems of vector-borne diseases: deterioration of capabilities are in accordance with the health sector. public health infrastructure, lack of adequate funding. Other available human resources are not suitable for lack of adequate training and training models, over- malaria management. Frequent job mutations cause specialization in biomedical sciences, driven by the inconsistency in malaria control. Malaria control based advent of technology and emphasis on basic sciences, on case data is going well, but the observation of malaria and bureaucratization. If IVM is to be successfully vectors is not carried out continuously so that the early integrated into national malaria control programs, these warning system is not effective. (Gyapong et al. shortcomings must be overcome. The lack of an 2. ,(Breman et al. , 2. integrated malaria management program is caused by a Media sectors only support malaria government system that does not allow cross-agency Media-based publics and culture-based publics are programs and budgeting. It is hoped that the evaluation the fourth subsystem, media-based publics and culture- of IVM can be improved for new program proposals on based publics, integrating and combining two forms of On the one hand, this helix, through culture- government side. Each based publics . g: traditions, values, etc. ), has social On the other hand, media-based public helices performance indicators. Financial responsibility and . : television, internet, newspapers, etc. ) also contain program success are sectoral (Smith et al. , 2. It is not 'information capital' . : news, communication, social easy to develop an integrated program, which means that malaria control cannot be carried out effectively(Gilroy Witsqa Firmansyah. Yura, et. A Narrative Review: Quintuple Helixs Model for Malaria Elimination JKM : Jurnal Kesehatan Mahardika Vol. No. September 2022, pp. ISSN: 2355-0724. DOI: 10. 54867/jkm. Media is an important index in handling malaria in an needs, problems, or satisfaction of citizens as an output area because not all people fully understand malaria. In a into politics or the political system. The output of different context but still in the realm of health knowledge from the media-based and culture-based promotion. Dwilaksono once said the same thing that public is something new. (Goodman et al. , 2. information media within the scope of communication in Environment the form of social networking media is very effective for information targeting Gilroy and colleagues reported a reduction in malaria teenagers and incidence and sporozoite prevalence rates in Nigeria productive ages. Although in terms of age, the people using a variety of environmental management techniques, who became respondents in this study were not in their including source reduction and drainage25. Utzinger and teens but were still of productive age, in general it can be colleagues reviewed environmental management (EM) said that the communication media, namely television, activities in suburban habitat, cities and disturbed land had a good influence on their knowledge of the concept areas, around the Zambian Copper mine. Significant of malaria. reductions in malaria transmission were achieved over a The information conveyed and received well by the three-to-five-year period, using a combination of community was able to influence the level of public drainage, larval habitat filling, and bed netting. Keizer knowledge about the concept of malaria where malaria is and colleagues conducted a meta-analysis of EM studies a curable disease. In general, it can be said that the globally and concluded that EM can have a significant communication media that have been used by the public impact on clinical malaria if EM is compatible with eco- as entertainment media can be used as information media epidemiological settings. EM was also used with by agencies related to health to promote or convey available larvicides to control malaria in the coastal city information on health programs in controlling malaria of Mombasa(Goodman et al. , 1999. Partz et al. , 2000. and other diseases. Raharjo, 2. The output of the natural environment is followed by A combination of water drainage techniques and the input of new knowledge about nature and a green larvicides reduced the number of malaria cases by 98% . lifestyle for media-based and culture-based from 1969 to 1970 in the coastal floodplains of Haiti. public subsystems. In this helix it is very important to India. Sharma and colleagues reported a more than 95% communicate and lead a green lifestyle. Here, the media- reduction in malaria incidence over a four-year period based public receives a new and important function for communities receiving a combination of water . amely, information capita. , which spreads through the resource reduction activities and biological control in media information about the new green consciousness larval habitats. Collectively, these studies suggest that and new human lifestyle. This capital should provide several vector control strategies may be beneficial when incentives for how green lifestyles can be implemented used in combination. Further evaluation is needed to test in a simple, affordable, and conscious way . the effectiveness of IVM for reducing malaria in Africa. knowledge creatio. The absence of evaluation of IVM, as well as evaluation This knowledge creation promotes the necessary of intervention packages, has been noted recently by social capital of a culture-based society, on which society several investigators. (Campbell et al. , 2015. Metcalf and depends for sustainable development. Therefore, this Novak, 1994. Morens, 2008. Protopopoff et al. , 2. social capital must convey information about the wants. Witsqa Firmansyah. Yura, et. A Narrative Review: Quintuple Helixs Model for Malaria Elimination JKM : Jurnal Kesehatan Mahardika Vol. No. September 2022, pp. ISSN: 2355-0724. DOI: 10. 54867/jkm. Implementation of the quintuple helix model requires demande. at the national level, as a result of malaria assessing the need for vector control capabilities through cases, and if, for example, more targeted investments in policy requirements, reforms and adjustments to the policy framework that provides an enabling environment A certain quintuple helix begins to flow, so there will for vector control. Institutional development needs: be a positive impact. on all other subsystems and on strengthening of existing institutions and arrangements society as a whole. The quintuple helix model suggests that investment in knowledge and promotion of (Sharma and Sharma, 1986. W and Novak, 2. knowledge production brings a new and important Managerial development needs: establishment of impetus to innovation, knowledge, and the advancement clear criteria and decision-making procedures for Technical By taking small steps towards sustainability, a long- strengthening: development of technical facilities to term and leading knowledge society can emerge, one that support vector control programs. Human resource will live in balance with nature and ultimately, perhaps, development needs: formation and training of employees lead to a green economy miracle. Mastering and Community balancing issues such as malaria are often portrayed and this will ensure the sustainability of the presented as a theme of survival for humanity in a global control approach. (IPPC, 2. As a result. of society. Apart from implementing the quintuple helix model. The quintuple helix innovation model bridges social environmental management can also be carried out in ecology with knowledge production and innovation. order to maximize malaria prevention. Environmental Here, the natural environment of society and the economy is not only a challenge, but also encourages and manipulate the environment or its interaction with inspires knowledge production and innovation. In the humans, which aims to prevent, limit vector reproduction, quintuple helix innovation model approach, the natural and reduce mosquito-human contact. Environmental environment of society is identified as an opportunity to modification is an environmental management effort that push further and excel in sustainable development and includes permanent physical changes to water and plants, the coevolution of the knowledge economy, knowledge which aims to prevent, eliminate, or reduce vector society, and knowledge democracy. habitat without disturbing the quality of the environment for human life. These activities can be in the form of REFERENCE